Cannabinoids in animals models do which is one reason that led them to pursue the investigation of medical marijuana and HIV. Pain is the number one reason people seek medical treatment and patients seeking pain relief are the most prevalent group employing cannabis medicines.

A typical observation by patients is that their use of cannabis doesn’t necessarily take away the pain, but that they are no longer preoccupied with the pain; they are able to ignore it.

In cases of inflammatory pain, cannabis decreases the inflammation that causes the pain.

Many chronic pain patients have been prescribed strong opioids such as oxycontin, morphine, or hydrocodone to manage their pain.